///可编辑listview类
using System;
using System.Collections.Generic;
using System.Linq;
using System.Text;
using System.Windows.Forms;
using System.Drawing;
using System.Runtime.InteropServices;

namespace testlistview
{
    public class ListViewCell
    {
       ///
       /// 单元格所在的行。
       ///
       public ListViewItem Item { get; set; }
       ///
       /// Item 的 Index 值会变成 -1，暂时未找到原因，用这个代替。
       ///
       public int ItemIndex { get; set; }
       ///
       /// 单元格所在的列。
       ///
       public ColumnHeader Column { get; set; }
       ///
       /// 单元格相对于 ListView 的大小和位置。
       ///
       public Rectangle Bounds { get; set; }
    }


    public class ListViewCellLocator
    {
       [DllImport("user32")]
       public static extern int GetScrollPos(int hwnd, int nBar);


       ///
       /// 根据位置 x、y 获得 ListViewCell。
       ///
       ///
       /// 工作区坐标表示的 x 轴坐标。
       /// 工作区坐标表示的 y 轴坐标。
       ///
       public static ListViewCell GetCell(ListView listView, int x, int y)
       {
          ListViewCell cell = new ListViewCell();

           // 获得单元格所在的行。
           cell.Item = listView.GetItemAt(x, y);
           if (cell.Item == null)
           {
              return null;
           }
          cell.ItemIndex = cell.Item.Index; // 现在 Item.Index 还能用

           // 根据各列宽度，获得单元格所在的列，以及 Bounds。
           int currentX = cell.Item.GetBounds(ItemBoundsPortion.Entire).Left; // 依次循环各列，表示各列的起点值
           int scrollLeft = GetScrollPos(listView.Handle.ToInt32(), 0); // 可能出现了横向滚动条，左边隐藏起来的宽度
           for (int i = 0; i < listView.Columns.Count; i++)
           {
              if (scrollLeft + x >= currentX &&
                 scrollLeft + x < currentX + listView.Columns[i].Width)
              {
                 cell.Column = listView.Columns[i]; // 列找到了
                 Rectangle itemBounds = cell.Item.GetBounds(ItemBoundsPortion.Entire);
                 cell.Bounds = new Rectangle(currentX,
                    itemBounds.Y,
                    listView.Columns[i].Width,
                    itemBounds.Height);
                 break;
              }
              currentX += listView.Columns[i].Width;
           }

           if (cell.Column == null)
           {
              return null;
           }
           return cell;
       }
    }
    public class EditableListViewSubmittingEventArgs : EventArgs
    {
       public ListViewCell Cell { get; set; }
       public string Value { get; set; }
    }
    public delegate void EditableListViewSubmitting(object sender, EditableListViewSubmittingEventArgs e);
    class EditableListView
    {
       public event EditableListViewSubmitting Submitting;

       private ListView ListView { get; set; }
       private Point MousePosition = new Point();
       private TextBox EditBox { get; set; }
       public int[] TextBoxColumns { get; set; }

       public EditableListView(ListView listView)
       {
           // 初始化 EditBox
           EditBox = new TextBox();
          EditBox.Visible = false;
          EditBox.KeyUp += new KeyEventHandler(KeyUpHandle);
          EditBox.LostFocus += new EventHandler(EditBox_LostForcus);
           // 设置 ListView
           ListView = listView;
          ListView.MouseMove += new MouseEventHandler(delegate(object sender, MouseEventArgs e)
           {
              // 记录鼠标位置，便于在鼠标动作中使用（有些鼠标动作，比如双击，事件中并不传递鼠标双击时的位置）。
              MousePosition.X = e.X;
              MousePosition.Y = e.Y;
           });

          EditBox.Parent = ListView;

           // 事件
          ListView.DoubleClick += new EventHandler(EditItem);
       }

       private void KeyUpHandle(object sender, KeyEventArgs e) {
           if (e.KeyCode == Keys.Escape)
           {
              LeaveEdit();
           }
           else if (e.KeyCode == Keys.Enter)
           {
              SaveEdit();
           }
       }
       private void EditBox_LostForcus(object sender, EventArgs e) {
          SaveEdit();
       }
       private void SaveEdit() {
           if (Submitting != null)
           {
             EditableListViewSubmittingEventArgs args = new EditableListViewSubmittingEventArgs();
              if (EditBox.Tag != null)
              {
                 args.Cell = (ListViewCell)EditBox.Tag;
              }
              else
              {
                 args.Cell = null;
              }
              args.Value = EditBox.Text;
              LeaveEdit();
              Submitting(ListView, args);
           }
       }

       private void EditItem(object sender, EventArgs e) {
          ListViewCell cell = ListViewCellLocator.GetCell(this.ListView, MousePosition.X, MousePosition.Y);

           if (cell == null)
           {
              return;
           }

           if (TextBoxColumns.Contains(cell.Column.Index))
           {
              // 设置 EditBox 的位置、大小、内容、可显示等。
              EditBox.Bounds = cell.Bounds;
              EditBox.Text = cell.Item.SubItems[cell.Column.Index].Text;
              EditBox.Visible = true;
              EditBox.Focus();
              EditBox.Tag = cell;
           }
       }

       public bool IsEditableColumn(int columnIndex)
       {
           if (TextBoxColumns.Contains(columnIndex))
           {
              return true;
           }

           return false;
       }


       public void LeaveEdit()
       {
          EditBox.Visible = false;
          EditBox.Tag = null;
       }
    }
}

///窗体类form1.cs
using System;
using System.Collections.Generic;
using System.ComponentModel;
using System.Data;
using System.Drawing;
using System.Linq;
using System.Text;
using System.Windows.Forms;

namespace testlistview
{
    public partial class Form1 : Form
    {
       private EditableListView list;
       public Form1()
       {
          InitializeComponent();
       }

       private void Form1_Load(object sender, EventArgs e)
       {
          listView1.Columns.Add("测试");
          listView1.Columns.Add("测试12");
          ListViewItem lvi = new ListViewItem();
           lvi.Text = "第一列";
          lvi.SubItems.Add("第二列");
          listView1.Items.Add(lvi);
           list = new EditableListView(listView1);
          list.TextBoxColumns = new int[] {0, 1, 2, 3 };
          list.Submitting += new EditableListViewSubmitting(listViewSaveEditHandler); 
       }

       private void listViewSaveEditHandler(object sender, EditableListViewSubmittingEventArgs e)
       {
           if (e.Cell == null)
           {
              return;
           }
           string value = e.Value;
          ListViewItem item = e.Cell.Item;
           int itemindex = e.Cell.Column.Index;
          item.SubItems[itemindex].Text = value;
       }
    }
}

plus：如果第二列不能编辑 可以将listview1控件的FullRowSelect属性改为true